January 30, 2009 — Initial treatment with placebo in teens participating in antidepressant trials is not harmful, and in fact, adolescents who receive placebo prior to active treatment fare as well as those who receive immediate active treatment, a new study suggests.
Data from the 36-week Treatment for Adolescents With Depression Study (TADS) reveal that teens randomized to 12 weeks of placebo followed by active treatment had adverse events and end-of-study treatment response similar to those who received active treatment for the entire study duration.
“Our findings suggest that patients treated with placebo acutely are not harmed and that placebo is an acceptable intervention in randomized controlled trials with adolescents who have moderate or severe depression,” lead author Betsy D. Kennard, PsyD, from the University of Texas Southwestern Medical Center at Dallas, told Medscape Psychiatry.
This is the case dear friends, because the truth is that antidepressants virtually never out-perform placebo by any sigficant margin in any case. The reporting of this news and then still pretending there is any advantage to using antidepressants, is again, criminal in my opinion. These kids who are doing fine on placebo are promptly put on active drug as soon as possible they say. Can’t let them go untreated!! Why can’t people see what is right in front of their faces?? It’s so hard for me to fathom. And sometimes when I think about all the damage caused it just sickens me so profoundly I don’t know what to do.
But I guess, I’m here doing what I need to do. For now.
Have a nice weekend.