The second thing to know about neuroplasticity is that the most powerful way to change your brain is not actually medication, it's actually behavior, because that is what it was designed to change in relation to. And not just any behavior but specifically mental behavior or mental habit. One of the things she points out is that we create our neural networks. A heavily self-critical neural network which then gets reinforced through habit leads to depression (as well as other not so nice habits). This is important to understand.