Mind-boggling to me that this isn’t a no-brainer. When my psychiatrist started asking me when I’d have children I told him it was ridiculous to consider having children while on drugs…I knew even 25 years ago that it was a high risk I wouldn’t impose on an innocent life. Never mind that the Risperdal also rendered me infertile (by nature of the fact that I did not menstruate for 15 years) Harmless drugs, NOT. … [click on title to read and view more]
A critique of genetic research on schizophrenia – expensive castles in the air
Thank you Joanna Moncrieff!
“To me, the fact that genetics contributes little to our risk of disease, or our likelihood of developing behavioural and mental disturbance, seems a matter of celebration. The idea that we are doomed by our genetic make-up to develop life-threating or disabling conditions is surely a profoundly depressing one.”
In the light of the much trumpeted claims that recent research has identified genes for schizophrenia, it is important to review the track record of this type of endeavour (1). Despite thousands of studies costing millions of dollars, and endless predictions that the genetics of schizophrenia would shortly be revealed, the field has so far failed to identify any genes that substantially increase the risk of developing schizophrenia.
Following the advent of molecular genetics, some studies started to find weak associations between this or that gene and being diagnosed with schizophrenia, but attempts to replicate the findings generally failed. A large genome wide association study published in 2008, for example, analysed the distribution of 833 single nuclear polymorphisms (SNPs) in 14 genes that were thought to be the most likely ‘candidates’ for being associated with schizophrenia in a sample of 1,870 people with schizophrenia and 2002 controls. The study found…
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Shame: a painful emotion caused by a strong sense of guilt, embarrassment, unworthiness, or disgrace
I think of shame as an unclean emotion. It's laden with ideas of unworthiness and inferiority that are separate from the root emotions. These ideas attached to emotions, make shame extra tricky to sort out. Pure emotions without the baggage are much easier to deal with, process and integrate. It's worth thinking about shame and how we experience it. … [click on title to read and view more]
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