“The FDA notified health care professionals and patients about the increased risk of neural tube defects and other major birth defects, such as craniofacial defects and cardiovascular malformations, in babies exposed to valproate sodium and related products (valproic acid and divalproex sodium) during pregnancy. Healthcare practitioners should inform women of childbearing potential about these risks, and consider alternative therapies, especially if using valproate to treat migraines or other conditions not usually considered life-threatening.
“Women of childbearing potential should only use valproate if it is essential to manage their medical condition. Those who are not actively planning a pregnancy should use effective contraception, as birth defect risks are particularly high during the first trimester, before many women know they are pregnant.” (FDA notice)
Remember Philip is fundraising now and often notifies us of these issues first. Thanks Philip.
Oh, by the way, my doc encouraged me to get pregnant ALL THE TIME while on depakote and 4 other drugs too. Good man. Thought I’d be a good mom. Luckily I was a good mom and never had those babies.